Specifics of oxidative stress and antioxidant system in children with Crohn disease and ulcerative colitis

The results of studies the level biomarkers oxidative stress and antioxidant system in children with Crohn’s disease ulcerative colitis are presented. relationship between nosology feature redox imbalance was demonstrated, which proved by a significant difference reduced glutathione erythrocytes groups subjects. Children have lower erythrocyte compared to patients colitis. This pattern can be explained different types inflammation these diseases. has productive granulomatous chronic inflammation, one mechanisms development flow is incomplete phagocytosis. Oxidative deficiency glutathione, part system, make large contribution defect phagocytosis, persistence will lead an increase activity due preservation immune dysregulation. study presents variant using binary logistic regression search for model method differential diagnosis inflammatory bowel diseases, where independent variable content glutathione.